Krisztina Tar - ODT Personal data sheet


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Personal data sheet

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personal data approved: 2024. V. 08.

Personal data

name	Krisztina Tar
name of institution	University of Debrecen
doctoral school	DE Doctoral School of Molecular Medicine (Supervisor Az oktató valamelyik doktori iskolában egy vagy több doktorandusz vagy doktorjelölt munkáját irányítja. )
the share of work in the different doctoral schools.	DE Doctoral School of Molecular Medicine 100%
accreditation statement submitted to:	University of Debrecen

Contact details
E-mail address	tarkmed.unideb.hu
phone number	+36 52 412-345

Academic title
scientific degree, title	Ph.D.
year degree was obtained	2005
discipline to which degree belongs	theoretical medicine
institution granting the degree	University of Debrecen
scientific degree, title	Habilitation
year degree was obtained	2023
discipline to which degree belongs	theoretical medicine
institution granting the degree	University of Debrecen

Employment
2014 -	University of Debrecen university professor or researcher

Thesis topic supervisor

number of doctoral students supervised until now

number of students who fulfilled course requirements

students who obtained their degrees:

	Abdennour Douida	PhD	2021	DSMM-UD
	Azzam Aladdin	PhD	2021	DSMM-UD

completed course requirement:

Marvi Ghani

(PhD)

2022/08

DSMM-UD

present PhD students:

Hailemariam Amsalu Demlew

(PhD)

(2026/08)

DSMM-UD

Thesis topic proposals

Research
research area	cell- and molecular biology, biochemistry, proteasome, mitochondria, Blm10/PA200 proteasomal subunit, posttranslational modification of Drp1, neurodegenerative disease, Huntington disease
research field in which current research is conducted	biology theoretical medicine

Publications

2024

Ghani Marvi, Zohar Peleg, Ujlaki Gyula, Tóth Melinda, Amsalu Hailemariam, Póliska Szilárd, Tar Krisztina: Stable knockdown of Drp1 improves retinoic acid-BDNF-induced neuronal differentiation through global transcriptomic changes and results in reduced phosphorylation of ERK1/2 independently of DUSP1 and 6, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 12: pp. 1-25.
type of document: Journal paper/Article
language: English
URL

2021

Douida Abdennour, Batista Frank, Boto Pal, Regdon Zsolt, Robaszkiewicz Agnieszka, Tar Krisztina: Cells Lacking PA200 Adapt to Mitochondrial Dysfunction by Enhancing Glycolysis via Distinct Opa1 Processing, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22: (4) 1629
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL

2020

Douida A, Batista F, Robaszkiewicz A, Boto P, Aladdin A, Szenykiv M, Czinege R, Virág L, Tar K: The proteasome activator PA200 regulates expression of genes involved in cell survival upon selective mitochondrial inhibition in neuroblastoma cells, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 24: (12) pp. 6716-6730.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL

2020

Lontay B, Kiss A, Virág L, Tar K: How do post-translational modifications influence the pathomechanistic landscape of Huntington’s disease? A comprehensive review, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21: (12) 4282
type of document: Journal paper/Review paper
number of independent citations: 18
language: English
URL

2020

Aladdin Azzam, Yao Yanhua, Yang Ciyu, Kahlert Günther, Ghani Marvi, Király Nikolett, Boratkó Anita, Uray Karen, Dittmar Gunnar, Tar Krisztina: The Proteasome Activators Blm10/PA200 Enhance the Proteasomal Degradation of N-Terminal Huntingtin, BIOMOLECULES 10: (11) p. 1581.
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL

2019

Aladdin A, Király R, Boto P, Regdon Zs, Tar K: Juvenile Huntington’s disease skin fibroblasts respond with elevated parkin level and increased proteasome activity as a potential mechanism to counterbalance the pathological consequences of mutant Huntingtin protein, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20: 5338
type of document: Journal paper/Article
number of independent citations: 9
language: English
URL

2014

Tar K, Dange T, Yang C, Yao Y, Bulteau AL, Fernandez Salcedo E, Braigen S, Bouillaud F, Finley D, Schmidt M: Proteasomes associated with the Blm10 Activator Protein Antagonize Mitochondrial Fission Through Degradation of the Fission Protein Dnm1., JOURNAL OF BIOLOGICAL CHEMISTRY 289: (17) pp. 12145-12156.
type of document: Journal paper/Article
number of independent citations: 7
language: English
URL

2011

Lopez AD, Tar K, Krugel U, Dange T, Ros IG, Schmidt M: Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10., MOLECULAR BIOLOGY OF THE CELL 22: (5) pp. 528-540.
type of document: Journal paper/Article
number of independent citations: 17
language: English
DOI

2011

Kruegel U, Robison B, Dange T, Kahlert G, Delaney JR, Kotireddy S, Tsuchiya M, Tsuchiyama S, Murakami CJ, Schleit J, Sutphin G, Carr D, Tar K, Dittmar G, Kaeberlein M, Kennedy BK, Schmidt M: Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae., PLOS GENETICS 7: (9) p. e1002253.
type of document: Journal paper/Article
number of independent citations: 42
language: English
DOI

2010

Pospisilik JA, Schramek D, Schnidar H, Cronin SJ, Nehme NT, Zhang X, Knauf C, Cani PD, Aumayr K, Todoric J, Bayer M, Haschemi A, Puviindran V, Tar K, Orthofer M, Neely GG, Dietzl G, Manoukian A, Funovics M, Prager G, Wagner O, Ferrandon D, Aberger F, Hui CC, Esterbauer H, Penninger JM: Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate., CELL 140: (1)
type of document: Journal paper/Article
number of independent citations: 106
language: English
DOI

Number of independent citations to these publications:

208

Scientometric data

list of publications and citations

number of scientific publications that meet accreditation criteria:

number of scientific publications:

monographs and professional books:

monographs/books in which chapters/sections were contributed:

scientific publications published abroad that meet the accreditation criteria:

publications not in Hungarian, published in Hungary, meeting the accreditation criteria:

number of independent citations to scientific publications and creative works:

780