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personal data approved: 2020. VI. 08.
Personal data
Krisztina Tar
name Krisztina Tar
name of institution
doctoral school
DE Doctoral School of Molecular Medicine (Supervisor)
accreditation statement submitted to: University of Debrecen
Contact details
E-mail address tarkmed.unideb.hu
phone number +36 52 412-345
Academic title
scientific degree, title Ph.D.
year degree was obtained 2005
discipline to which degree belongs theoretical medicine
institution granting the degree University of Debrecen
Employment
2014 - University of Debrecen
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now
number of students who fulfilled course requirements
students who obtained their degrees:
completed course requirement:
Abdennour Douida (PhD) 2020/08  DSMM-UD
Azzam Aladdin (PhD) 2021/01  DSMM-UD
present PhD students:
Marvi Ghani (PhD) (2022/08)  DSMM-UD
  Thesis topic proposals
Research
research area cell- and molecular biology, biochemistry, proteasome, mitochondria, Blm10/PA200 proteasomal subunit, posttranslational modification of Drp1, neurodegenerative disease, Huntington disease
research field in which current research is conducted biology
theoretical medicine
Publications
2020

Douida A, Batista F, Robaszkiewicz A, Boto P, Aladdin A, Szenykiv M, Czinege R, Virág L, Tar K: The proteasome activator PA200 regulates expression of genes involved in cell survival upon selective mitochondrial inhibition in neuroblastoma cells, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 24: pp. 6716-6730.
type of document: Journal paper/Article
language: English
URL 
2020

Lontay B, Kiss A, Virág L, Tar K: How do post-translational modifications influence the pathomechanistic landscape of Huntington’s disease? A comprehensive review, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21: pp. 1-34.
type of document: Journal paper/Review paper
language: English
URL 
2020

Alatshan Ahmad, Kovács Gergő E., Aladdin Azzam, Czimmerer Zsolt, Tar Krisztina, Benkő Szilvia: All-Trans Retinoic Acid Enhances both the Signaling for Priming and the Glycolysis for Activation of NLRP3 Inflammasome in Human Macrophage, CELLS 9: (7) 1591
type of document: Journal paper/Article
language: English
URL 
2020

Aladdin Azzam, Yao Yanhua, Yang Ciyu, Kahlert Günther, Ghani Marvi, Király Nikolett, Boratkó Anita, Uray Karen, Dittmar Gunnar, Tar Krisztina: The Proteasome Activators Blm10/PA200 Enhance the Proteasomal Degradation of N-Terminal Huntingtin, BIOMOLECULES 10: (11) p. 1581.
type of document: Journal paper/Article
language: English
URL 
2019

Aladdin A, Király R, Boto P, Regdon Zs, Tar K: Juvenile Huntington’s disease skin fibroblasts respond with elevated parkin level and increased proteasome activity as a potential mechanism to counterbalance the pathological consequences of mutant Huntingtin protein, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20: pp. 1-27.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL 
2014

Tar K, Dange T, Yang C, Yao Y, Bulteau AL, Fernandez Salcedo E, Braigen S, Bouillaud F, Finley D, Schmidt M: Proteasomes associated with the Blm10 Activator Protein Antagonize Mitochondrial Fission Through Degradation of the Fission Protein Dnm1., JOURNAL OF BIOLOGICAL CHEMISTRY 289: (17) pp. 12145-12156.
type of document: Journal paper/Article
number of independent citations: 7
language: English
URL 
2011

Lopez AD, Tar K, Krugel U, Dange T, Ros IG, Schmidt M: Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10., MOLECULAR BIOLOGY OF THE CELL 22: (5) pp. 528-540.
type of document: Journal paper/Article
number of independent citations: 17
language: English
DOI 
2011

Kruegel U, Robison B, Dange T, Kahlert G, Delaney JR, Kotireddy S, Tsuchiya M, Tsuchiyama S, Murakami CJ, Schleit J, Sutphin G, Carr D, Tar K, Dittmar G, Kaeberlein M, Kennedy BK, Schmidt M: Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae., PLOS GENETICS 7: (9) p. e1002253.
type of document: Journal paper/Article
number of independent citations: 42
language: English
DOI 
2010

Pospisilik JA, Schramek D, Schnidar H, Cronin SJ, Nehme NT, Zhang X, Knauf C, Cani PD, Aumayr K, Todoric J, Bayer M, Haschemi A, Puviindran V, Tar K, Orthofer M, Neely GG, Dietzl G, Manoukian A, Funovics M, Prager G, Wagner O, Ferrandon D, Aberger F, Hui CC, Esterbauer H, Penninger JM: Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate., CELL 140: (1)
type of document: Journal paper/Article
number of independent citations: 106
language: English
DOI 
2006

Tar K, Csortos C, Czikora I, Olah G, Ma SF, Wadgaonkar R, Gergely P, Garcia Jgn, Verin AD: Role of Protein Phosphatase 2A in The Regulation of Endothelial Cell Cytoskeleton Structure, JOURNAL OF CELLULAR BIOCHEMISTRY 98: (4) pp. 931-953.
type of document: Journal paper/Article
number of independent citations: 34
language: English
DOI 
Number of independent citations to these publications:207 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
17
number of scientific publications:
17
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
scientific publications published abroad that meet the accreditation criteria:
17
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
0
number of independent citations to scientific publications and creative works:
543

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )