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personal data approved: 2020. V. 04.
Personal data
name Ádám Dénes
name of institution
doctoral school
ELTE Doctoral School of Biology (Academic staff member)
SE János Szentágothai Doctoral School of Neurosciences (Supervisor)
Contact details
E-mail address denesakoki.hu
phone number +36 1 210-9954
Academic title
scientific degree, title Ph.D.
year degree was obtained 2007
discipline to which degree belongs theoretical medicine
institution granting the degree Semmelweis University
Employment
2004 - MTA KOKI (research institute, not university)
other (not specified) (Tudományos főmunkatárs)
Thesis topic supervisor
number of doctoral students supervised until now 5
number of students who fulfilled course requirements 1.5
students who obtained their degrees:
(50%) Rodriguez-Grande Beatriz PhD 2014  
(50%) Hannah Buggey PhD 2013  
(50%) Caroline Drake PhD 2012  

completed course requirement, without degree or degree granting in process:
Bernadett Martinecz (PhD) 2018/08  JSDSN
(50%) Rebeka Fekete (PhD) 2016/08  JSDSN
present PhD students:
Tamás Szlepák (PhD) (2022/08)  JSDSN
(50%) Balázs Pósfai (PhD) (2021/08)  JSDSN
Eszter Császár (PhD) (2020/08)  JSDSN
  Thesis topic proposals
Research
research area The role of inflammation in diseases of the central nervous system. The role of microglia in the pathophysiology of stroke. Central autonomic innervation of immune organs.
research field in which current research is conducted theoretical medicine
biology
Publications
2020

Cserep C, Posfai B, Lenart N, Fekete R, Laszlo ZI, Lele Z, Orsolits B, Molnar G, Heindl S, Schwarcz AD, Ujvari K, Kornyei Z, Toth K, Szabadits E, Sperlagh B, Baranyi M, Csiba L, Hortobagyi T, Magloczky Z, Martinecz B, Szabo G, Erdelyi F, Szipocs R, Tamkun MM, Gesierich B, Duering M, Katona I, Liesz A, Tamas G, Denes A: Microglia monitor and protect neuronal function through specialized somatic purinergic junctions, SCIENCE 367: (6477) pp. 528-537.
type of document: Journal paper/Article
number of independent citations: 9
language: English
URL 
2019

Wong Raymond, Lénárt Nikolett, Hill Laura, Toms Lauren, Coutts Graham, Martinecz Bernadett, Császár Eszter, Nyiri Gábor, Papaemmanouil Athina, Waisman Ari, Müller Werner, Schwaninger Markus, Rothwell Nancy, Francis Sheila, Pinteaux Emmanuel, Denés Adam, Allan Stuart M.: Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons, BRAIN BEHAVIOR AND IMMUNITY 76: pp. 126-138.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2019

Helyes Zsuzsanna, Tékus Valéria, Szentes Nikolett, Pohóczky Krisztina, Botz Bálint, Kiss Tamás, Kemény Ágnes, Környei Zsuzsanna, Tóth Krisztina, Lénárt Nikolett, Ábrahám Hajnalka, Pinteaux Emmanuel, Francis Sheila, Sensi Serena, Dénes Ádám, Goebel Andreas: Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin-1-induced mechanisms, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116: (26) pp. 13067-13076.
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL 
2018

Fekete R, Cserep C, Lenart N, Toth K, Orsolits B, Martinecz B, Méhes Előd, Szabó Bálint, Németh Valéria, Gönci Balázs, Sperlagh B, Boldogkoi Z, Kittel A, Baranyi M, Ferenczi S, Kovacs K, Szalay G, Rozsa B, Webb C, Kovacs GG, Hortobagyi T, West BL, Kornyei Z, Denes A: Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms, ACTA NEUROPATHOLOGICA 136: (3) pp. 461-482.
type of document: Journal paper/Article
number of independent citations: 12
language: English
URL 
2016

Szalay G, Martinecz B, Lenart N, Kornyei Z, Orsolits B, Judak L, Csaszar E, Fekete R, West BL, Katona G, Rozsa B, Denes A: Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke, NATURE COMMUNICATIONS 7: 11499
type of document: Journal paper/Article
number of independent citations: 155
language: English
URL 
2015

Denes A, Coutts G, Lenart N, Cruickshank SM, Pelegrin P, Skinner J, Rothwell N, Allan SM, Brough D: AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112: (13) pp. 4050-4055.
type of document: Journal paper/Article
number of independent citations: 97
language: English
URL 
2015

Szigeti K, Horvath I, Veres DS, Martinecz B, Lenart N, Kovacs N, Bakcsa E, Marta A, Semjeni M, Mathe D, Denes A: A novel SPECT-based approach reveals early mechanisms of central and peripheral inflammation after cerebral ischemia., JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 35: (12) pp. 1921-1929.
type of document: Journal paper/Article
number of independent citations: 13
language: English
URL 
2014

Denes A, Pradillo JM, Drake C, Sharp A, Warn P, Murray KN, Rohit B, Dockrell D, Chamberlain J, Casbolt H, Francis S, Martinecz B, Nieswandt B, Rothwell N, Allan SM: Streptococcus pneumoniae worsens cerebral ischaemia via IL-1 and platelet GPIbalpha, ANNALS OF NEUROLOGY 75: (5) pp. 670-683.
type of document: Journal paper/Article
number of independent citations: 18
language: English
URL 
2010

Denes A, Humphreys N, Lane TE, Grencis R, Rothwell N: Chronic systemic infection exacerbates ischemic brain damage via a CCL5 (regulated on activation, normal T-cell expressed and secreted)-mediated proinflammatory response in mice, JOURNAL OF NEUROSCIENCE 30: (30) pp. 10086-10095.
type of document: Journal paper/Article
number of independent citations: 55
language: English
URL 
2008

Denes A, Ferenczi S, Halasz J, Kornyei Z, Kovacs KJ: Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 28: (10) pp. 1707-1721.
type of document: Journal paper/Article
number of independent citations: 185
language: English
URL 
Number of independent citations to these publications:550 
Scientometric data
Saját közlemény- és idézőlista list of publications and citations
number of scientific publications that meet accreditation criteria:
77
number of scientific publications:
77
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
1 
scientific publications published abroad that meet the accreditation criteria:
74
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
0
number of independent citations to scientific publications and creative works:
2791

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )