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Data sheet of PhD student
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Personal data
name András Tálas
name of institution Semmelweis University, Budapest
doctoral school SE Doctoral School of Molecular Medicine
Supervision
thesis supervisor Ervin Welker
one supervisor or with co-supervisor individual
degree PhD
starting of doctoral studies 2014
date of final certificate (year,month) 2017/08
year in which degree was obtained 2021
diszertáció Main findings in the thesis (in Hungarian)The thesis
data of the public discussion defense
Employment
2021 - Természettudományi Kutatóközpont
other (not specified) (Tudományos Munkatárs)
Publications
2022

Simon Dorottya Anna, Tálas András, Kulcsár Péter István, Biczók Zsuzsanna, Krausz Sarah Laura, Várady György, Welker Ervin: PEAR, a flexible fluorescent reporter for the identification and enrichment of successfully prime edited cells, ELIFE 11: e69504
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2022

Kulcsár P.I., Tálas A., Ligeti Z., Krausz S.L., Welker E.: SuperFi-Cas9 exhibits remarkable fidelity but severely reduced activity yet works effectively with ABE8e, NATURE COMMUNICATIONS 13: (1) 6858
type of document: Journal paper/Article
language: English
URL 
2021

Tálas András, Huszár Krisztina, Kulcsár Péter István, Varga Julia K, Varga Éva, Tóth Eszter, Welker Zsombor, Erdős Gergely, Pach Péter Ferenc, Welker Ágnes, Györgypál Zoltán, Tusnády Gábor E, Welker Ervin: A method for characterizing Cas9 variants via a one-million target sequence library of self-targeting sgRNAs, NUCLEIC ACIDS RESEARCH 49: (6) e31
type of document: Journal paper/Article
number of independent citations: 5
language: English
URL 
2021

Tálas András, Simon Dorottya A., Kulcsár Péter I., Varga Éva, Krausz Sarah L., Welker Ervin: BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors, NATURE COMMUNICATIONS 12: (1) 6353
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL 
2020

Tóth Eszter, Varga Éva, Kulcsár Péter István, Kocsis-Jutka Virág, Krausz Sarah Laura, Nyeste Antal, Welker Zsombor, Huszár Krisztina, Ligeti Zoltán, Tálas András, Welker Ervin: Improved LbCas12a variants with altered PAM specificities further broaden the genome targeting range of Cas12a nucleases, NUCLEIC ACIDS RESEARCH 48: (7) pp. 3722-3733.
type of document: Journal paper/Article
number of independent citations: 32
language: English
URL 
2020

Kulcsár Péter István, Tálas András, Tóth Eszter, Nyeste Antal, Ligeti Zoltán, Welker Zsombor, Welker Ervin: Blackjack mutations improve the on-target activities of increased fidelity variants of SpCas9 with 5′G-extended sgRNAs, NATURE COMMUNICATIONS 11: (1) 1223
type of document: Journal paper/Article
number of independent citations: 10
language: English
URL 
2018

Tóth Eszter, Czene Bernadett C, Kulcsár Péter I, Krausz Sarah L, Tálas András, Nyeste Antal, Varga Éva, Huszár Krisztina, Weinhardt Nóra, Ligeti Zoltán, Borsy Adrienn É, Fodor Elfrieda, Welker Ervin: Mb- and FnCpf1 nucleases are active in mammalian cells: activities and PAM preferences of four wild-type Cpf1 nucleases and of their altered PAM specificity variants, NUCLEIC ACIDS RESEARCH 46: (19) pp. 10272-10285.
type of document: Journal paper/Article
number of independent citations: 41
language: English
URL 
2017

Tálas András, Péter Istvan Kulcsár, Nóra Weinhardt, Adrienn Borsy, Eszter Tóth, Kornélia Szebényi, Sarah Laura Krausz, Krisztina Huszár, István Vida, Ádám Sturm, Bianka Gordos, Orsolya Ivett Hoffmann, Petra Bencsura, Antal Nyeste, Zoltán Ligeti, Elfrieda Fodor, Ervin Welker: A convenient method to pre-screen candidate guide RNAs for CRISPR/Cas9 gene editing by NHEJ-mediated integration of a 'self-cleaving' GFP-expression plasmid, DNA RESEARCH 24: (6) pp. 609-621.
type of document: Journal paper/Article
number of independent citations: 12
language: English
URL 
2017

Kulcsar PI, Talas A, Huszar K, Ligeti Z, Toth E, Weinhardt N, Fodor E, Welker E: Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage, GENOME BIOLOGY 18: 190
type of document: Journal paper/Article
number of independent citations: 69
language: English
URL 
2016

Toth E, Weinhardt N, Bencsura P, Huszar K, Kulcsar PI, Talas A, Fodor E, Welker E: Cpf1 nucleases demonstrate robust activity to induce DNA modification by exploiting homology directed repair pathways in mammalian cells, BIOLOGY DIRECT 11: 46
type of document: Journal paper/Article
number of independent citations: 39
language: English
URL 
Number of independent citations to these publications:211 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
 
number of scientific publications:
 
monographs and professional books:
 
monographs/books in which chapters/sections were contributed:
 
number of independent citations to scientific publications and creative works:
 
Research
research area Genome engineering
research field in which current research is conducted biology

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )