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personal data approved: 2022. XI. 28.
Personal data
András Szabó
name András Szabó
name of institution
doctoral school
DE Doctoral School of Molecular Cellular and Immune Biology (Supervisor)
the share of work in the different doctoral schools. DE Doctoral School of Molecular Cellular and Immune Biology 100%
accreditation statement submitted to: University of Debrecen
Contact details
E-mail address andrasszabomed.unideb.hu
phone number +36 52 416-432/66535
Academic title
scientific degree, title Ph.D.
year degree was obtained 2009
discipline to which degree belongs biology
institution granting the degree University of Szeged
Employment
2016 - University of Debrecen
egyetemi kutató
Thesis topic supervisor
number of doctoral students supervised until now 2
number of students who fulfilled course requirements 1
students who obtained their degrees:
Vanda Toldi PhD 2022  DSMCI

present PhD students:
Nataly Morales Granda (PhD) (2025/08)  DSMCI
  Thesis topic proposals
Research
research area The genetic risk factors of chronic pancreatitis
research field in which current research is conducted theoretical medicine
biology
Publications
2021

Szabó András, Toldi Vanda, Gazda Lívia Diána, Demcsák Alexandra, Tőzsér József, Sahin-Tóth Miklós: Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis, JOURNAL OF BIOLOGICAL CHEMISTRY 296: 100343
type of document: Journal paper/Article
number of independent citations: 5
language: English
URL 
2021

Toldi Vanda, Kassay Norbert, Szabó András: Missense PNLIP mutations impeding pancreatic lipase secretion cause protein misfolding and endoplasmic reticulum stress, PANCREATOLOGY [Epub ahead of print]:
type of document: Journal paper/Article
language: English
URL 
2020

Toldi Vanda, Szabó András, Sahin-Tóth Miklós: Inactivation of mesotrypsin by chymotrypsin C prevents trypsin inhibitor degradation, JOURNAL OF BIOLOGICAL CHEMISTRY 295: (11) pp. 3447-3455.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2019

Lasher Denise, Szabo Andras, Masamune Atsushi, Chen Jian-Min, Xiao Xunjun, Whitcomb David C., Barmada M. Michael, Ewers Maren, Ruffert Claudia, Paliwal Sumit, Issarapu Prachand, Bhaskar Seema, Mani K. Radha, Chandak Giriraj R., Laumen Helmut, Masson Emmanuelle, Kume Kiyoshi, Hamada Shin, Nakano Eriko, Seltsam Katharina, Bugert Peter, Mueller Thomas, Groneberg David A., Shimosegawa Tooru, Rosendahl Jonas, Ferec Claude, Lowe Mark E., Witt Heiko, Sahin-Toth Miklos: Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis, AMERICAN JOURNAL OF GASTROENTEROLOGY 114: (6) pp. 974-983.
type of document: Journal paper/Article
number of independent citations: 8
language: English
URL 
2019

Esteghamat Fatemehsadat, Broughton James S, Smith Emily, Cardone Rebecca, Tyagi Tarun, Guerra Mateus, Szabó András, Ugwu Nelson, Mani Mitra V, Azari Bani, Kayingo Gerald, Chung Sunny, Fathzadeh Mohsen, Weiss Ephraim, Bender Jeffrey, Mane Shrikant, Lifton Richard P, Adeniran Adebowale, Nathanson Michael H, Gorelick Fred S, Hwa John, Sahin-Tóth Miklós, Belfort-DeAguiar Renata, Kibbey Richard G, Mani Arya: CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation., NATURE GENETICS 51: (8) pp. 1233-1243.
type of document: Journal paper/Article
number of independent citations: 5
language: English
URL 
2016

Szabo A, Pilsak C, Bence M, Witt H, Sahin-Toth M: Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2., JOURNAL OF BIOLOGICAL CHEMISTRY 291: (34) pp. 17706-17716.
type of document: Journal paper/Article
number of independent citations: 8
language: English
URL 
2015

Szabo Andras, Ludwig Maren, Hegyi Eszter, Szepeova Renata, Witt Heiko, Sahin-Toth Miklos: Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis, JOURNAL OF BIOLOGICAL CHEMISTRY 290: (28) pp. 17282-17292.
type of document: Journal paper/Article
number of independent citations: 12
language: English
URL 
2013

Batra J, Szabó A, Caulfield TR, Soares AS, Sahin-Tóth M, Radisky ES: Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation, JOURNAL OF BIOLOGICAL CHEMISTRY 288: (14) pp. 9848-9859.
type of document: Journal paper/Article
number of independent citations: 18
language: English
URL 
2012

Szabó A, Sahin-Tóth M: Determinants of chymotrypsin C cleavage specificity in the calcium-binding loop of human cationic trypsinogen, FEBS JOURNAL 279: (23) pp. 4283-4292.
type of document: Journal paper/Article
number of independent citations: 14
language: English
URL 
2012

Szabó A, Sahin-Tóth M: Increased activation of hereditarypancreatitis-associated Human cationic trypsinogen mutants inpresence of chymotrypsin C, JOURNAL OF BIOLOGICAL CHEMISTRY 287: (24) pp. 20701-20710.
type of document: Journal paper/Article
number of independent citations: 28
language: English
URL 
Number of independent citations to these publications:101 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
35
number of scientific publications:
34
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
number of independent citations to scientific publications and creative works:
573

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )