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Personal data sheet
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VALIDITY EXPIRED
personal data approved: 2017. XI. 27.
Personal data
Lajos Széles
name Lajos Széles
name of institution
doctoral school
DE Doctoral School of Molecular Cellular and Immune Biology (Supervisor)
the share of work in the different doctoral schools. DE Doctoral School of Molecular Cellular and Immune Biology 100%
accreditation statement submitted to: University of Debrecen
Contact details
E-mail address szeleslmed.unideb.hu
phone number +36 52 411-717
Academic title
scientific degree, title Ph.D.
year degree was obtained 2009
discipline to which degree belongs theoretical medicine
institution granting the degree University of Debrecen
Employment
2015 - University of Debrecen
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now
number of students who fulfilled course requirements
students who obtained their degrees:
Mária Nagyné Csumita PhD 2023  DSMCI
present PhD students:
Hamidreza Mianesaz (PhD) (2024/08)  DSMCI
  Thesis topic proposals
Research
research area Transcriptional regulation of immune responses
research field in which current research is conducted theoretical medicine
biology
Publications
2015

 Szeles Lajos, Meissner Felix, Dunand-Sauthier Isabelle, Thelemann Christoph, Hersch Micha, Singovski Simon, Haller Sergio, Gobet Florian, Marraco Silvia A Fuertes, Mann Matthias, Garcin Dominique, Acha-Orbea Hans, Reith Walter: TLR3-Mediated CD8(+) Dendritic Cell Activation Is Coupled with Establishment of a Cell-Intrinsic Antiviral State, JOURNAL OF IMMUNOLOGY 195: (3) pp. 1025-1033.
type of document: Journal paper/Article
language: English
DOI 
2013

 Gyongyosi A, Szatmari I, Pap A, Dezso B, Pos Z, Szeles L, Varga T, Nagy L: RDH10, RALDH2 and CRABP2 are required components of PPARg-directed all-trans-retinoic acid synthesis and signaling in human dendritic cells, JOURNAL OF LIPID RESEARCH 54: (9) pp. 2458-2474. pp. 2458-2474.
type of document: Journal paper/Article
number of independent citations: 6
language: English
URL 
2012

 Nagy L, Szanto A, Szatmari I, Széles L: Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response, PHYSIOLOGICAL REVIEWS 92: (2) pp. 739-789.
type of document: Journal paper/Review paper
number of independent citations: 57
language: English
DOI 
2011

 Poliska S, Csanky E, Szanto A, Szatmari I, Mesko B, Szeles L, Dezso B, Scholtz B, Podani J, Kilty I, Takacs L, Nagy L: COPD-specific gene expression signatures of alveolar macrophages and also peripheral blood monocytes overlap and correlate with lung function, RESPIRATION 81: (6) pp. 499-510.
type of document: Journal paper/Article
number of independent citations: 18
language: English
URL 
2011

 Nakken B, Varga T, Szatmari I, Szeles L, Gyongyosi A, Illarionov P, Dezso B, Gogolak P, Rajnavolgyi E, Nagy L: Peroxisome Proliferator-Activated Receptor gamma-Regulated Cathepsin D Is Required for Lipid Antigen Presentation by Dendritic Cells, JOURNAL OF IMMUNOLOGY 187: (1) pp. 240-247.
type of document: Journal paper/Article
number of independent citations: 9
language: English
URL 
2010

 Szeles L, Poliska S, Nagy G, Szatmari I, Szanto A, Pap A, Lindstedt M, Santegoets SJAM, Ruhl R, Dezso B, Nagy L: Research Resource: Transcriptome Profiling of Genes Regulated by RXR and Its Permissive and Nonpermissive Partners in Differentiating Monocyte-Derived Dendritic Cells, MOLECULAR ENDOCRINOLOGY 24: (11) pp. 2218-2231.
type of document: Journal paper/Article
number of independent citations: 24
language: English
URL 
2010

 Szanto A, Balint L B, Nagy Z, Barta E, Dezso B, Pap A, Szeles L, Poliska S, Oros M, Evans R M, Barak Y, Schwabe J, Nagy L: STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells, IMMUNITY 33: (5) pp. 699-712.
type of document: Journal paper/Article
number of independent citations: 97
language: English
URL 
2009

 Széles L, Keresztes G, Törőcsik D, Balajthy Z, Krenács L, Póliska Sz, Steinmeyer A, Zuegel A, Pruenster M, Rot A, Nagy L: 1,25-dihydroxyvitaminD3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype, JOURNAL OF IMMUNOLOGY 182: (4) pp. 2074-2083.
type of document: Journal paper/Article
number of independent citations: 91
language: English
DOI 
2007

 Szeles L, Torocsik D, Nagy L: PPARgamma in immunity and inflammation: cell types and diseases, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1771: (8) pp. 1014-1030.
type of document: Journal paper/Article
number of independent citations: 78
language: English
DOI 
2006

 Szatmari I, Vámosi G, Brazda P, Balint LB, Benko S, Széles L, Jeney V, Özvegy-Laczka G, Szántó A, Barta E, Balla J, Sarkadi B, Nagy L: PPARg reguleted ABCG2 expression confers cytoprotection to human dendritic cells, JOURNAL OF BIOLOGICAL CHEMISTRY 281: (33) pp. 23812-23823.
type of document: Journal paper/Article
number of independent citations: 110
language: English
DOI 
Number of independent citations to these publications:490 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
25
number of scientific publications:
25
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
number of independent citations to scientific publications and creative works:
1470

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )