témavezető: Homolya László
helyszín (magyar oldal): Molecular Cell Biology Research Group, Institute of Enzymology, RCNS, HAS Budapest, Hungary helyszín rövidítés: MTA
A kutatási téma leírása:
Polarized epithelial cells, covering the surface of the physiological interfaces, play a pivotal role in the control of transport processes across these barriers. A key feature for accomplishing this task is the proper and asymmetric localization of the participating components: transporter proteins, cytoskeletal elements, signaling molecules, etc. Our study aims to elucidate the cross talk between various signaling pathways involved in the complex process of cell polarization. We primarily focus on liver cells and the LKB1 kinase, which has special role in cell polarization.
előírt nyelvtudás: fluent English további elvárások: experience in basic biochemical and cell biology methods, as well as in microscopy is preferred