Thesis supervisor: Zoltán Hórvölgyi
Location of studies (in Hungarian): BME Fizikai Kémia és Anyagtudományi Tanszék Abbreviation of location of studies: BME
Description of the research topic:
Chitosan is a polysaccharide of natural origin that has a variety of applications in many industries due to its advantageous properties (biocompatibility, antibacterial property etc.). Chitosan and its chemically modified derivatives can be used as temporary anti-corrosion protective coatings; controlled drug delivery systems; antibacterial coatings and packaging materials due to their cationic property; and in wastewater treatment due to their excellent sorption properties. Its swelling properties and the permeability of its thin films are pH-dependent, which makes it an important model material in the research of responsive behaviours.
The research task of the PhD student is to develop chemically modified chitosan coatings that can be designed depending on the application conditions to have swelling properties (permeability), antiviral, antibacterial and water-repellent properties. During this research composite coatings made of chitosan and other (bio)polymers, inorganic microphases and molecules that are important for applications (inhibitors, dyes, therapeutic agents) will be synthesised and studied. For studying permeability, multi-layered, chitosan-containing hybrid coatings capable of drug storage and delivery will also be prepared.
The bulk properties of the coatings will be characterized by UV-Vis spectroscopy, FTIR- and Raman-spectroscopy, scanning angle reflectometry, electrochemical (impedance spectroscopy and polarization) methods and sorption (e.g. dye impregnation) tests. The surface properties will be studied by wettability measurements, scanning electron microscopy, atomic force microscopy and microbiological examinations."
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