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Thesis topic proposal
 
Dosimetric evaluation of robot-assisted Stereotactic Body Radiation Therapy

THESIS TOPIC PROPOSAL

Institute: Budapest University of Technology and Economics
physics
Doctoral School of Physics

Thesis supervisor: Gábor Stelczer
Location of studies (in Hungarian): Institute of Nuclear Techniques
Abbreviation of location of studies: BME


Description of the research topic:

Robot-assisted stereotactic body radiation therapy (rSBRT) is a modern irradiation technique for small tumors. Highly hypofractionated doses with steep gradient and high conformity are delivered with a robotic arm based linear accelerator (CyberKnife®). In Hungary, SBRT can be performed with conventional linear accelerator (LINAC), gamma knife or CyberKnife (CK). CyberKnife is a special SBRT delivery system that utilizes a robotic arm to precisely irradiate tumors, offering a non-invasive alternative to traditional surgery. The aim of the PhD research is to analyze the image guidance of CyberKnife and in addition to determine the safety margins for the target volumes. A further objective is to investigate the efficiency of treatment planning methods and to compare different dose calculation algorithms implemented in the treatment planning system. Furthermore, to perform dosimetric analysis of SBRT performed with a conventional linear accelerator and CyberKnife according to international SBRT clinical protocol such as the RTOG recommendation. SBRT technique relies on advanced imaging technologies such as CT or MR imaging to define the location and shape of the tumor. The use of MR images is required in many regions such as the brain, head-and-neck, liver and prostate. Therefore, well-developed MRI protocols are also needed in clinical work for radiotherapy.
Requirements:

Clinical experience in stereotactic body radiation therapy, with particular expertise in the use of various treatment planning and treatment delivery systems. Ability to assess dosimetric parameters of irradiation plans and determine quality requirements for clinical applicability. Ability to compile different protocols and guidelines for measurements. B2 level of English language is a basic requirement.

Required language skills: English
Number of students who can be accepted: 1

Deadline for application: 2024-05-31


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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