Thesis supervisor: Ákos Csonka
Location of studies (in Hungarian): University of Szeged Faculty of Medicine Department of Traumatology Abbreviation of location of studies: TRAUM
Description of the research topic:
The proportion of atypical femoral fractures has significantly increased in the past years; however their incidence remains low. Relative risk of patients with atypical femoral fractures (AFF) taking bisphosphonate is high. Atypical fracture patterns have occurred in patients who did not take BP hence other potential risk factors that might play a role in bone turnover should be taken into consideration. The pathomechanism of atypical fracture includes every factor that impairs replacement of previously developed microfractures with a new bone matrix by decreasing bone tissue remodelling. Basically any medication, chronic disease, genetic mutation or genetic alteration that decreases bone remodelling appears as a potential risk factor of AFF. We aim to elucidate the clinical features of atypical femoral fractures.
Required language skills: english Number of students who can be accepted: 1