Thesis supervisor: Erzsébet Melinda Tóth
Location of studies (in Hungarian): BRC Institute of Biochemistry Abbreviation of location of studies: SzBK
Description of the research topic:
Heat shock proteins (Hsps) are evolutionarily conserved chaperone proteins which are upregulated under different stress conditions and in various diseases, therefore they are promising therapeutic targets. In the current project our aim is to study the protective role of the small Hsp, Hsp27, especially focusing on cardio- and cerebrovascular dysfunctions, using our Hsp27 overexpressing transgenic mice and different disease model strains (a model of hyperlipidemia and a model of Alzheimer’s disease).
Required language skills: English Number of students who can be accepted: 1