Thesis supervisor: György Keserű
Location of studies (in Hungarian): BME Szerves Kémia és Technológia Tanszék Abbreviation of location of studies: BME
Description of the research topic:
GPCRs are among the most targeted receptors in drug discovery however due to the complex nature of their structure and signaling designing drugs with a favourable polypharmacological profile remains challenging. During the PhD work, our objective is to design and synthesize ligands for G-protein coupled receptor targets with beneficial polypharmacological profile. These compounds might serve as pharmacological tools to investigate the receptors and may provide starting points for drug development with improved adverse effect profile.
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