Thesis supervisor: Zoltán Péterfi
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12. Abbreviation of location of studies: ÁOK
Description of the research topic:
We known that in some cases, the microbial change it is associated with the development of metabolic diseases (diabetes mellitus, obesity, fatty liver) and can influence the response rate for anti-inflammatory therapy in inflammatory bowel diseases (ulcerative colitis, Crohn's disease). Changing the microbial profile of these patients is accompanied by a change in severity of these diseases, so a properly selected microbiota may result in the healing or temporary improvement of the patients. Only a few patients have had similar interventions on the subject, so the efficacy assessment and the donor selection criteria are not clear yet.
We would like to measure the effectiveness of microbial transplantation to reduce the insulin resistance, body weight, or fatty liver, or to reduce the need for medication in refractory bowel patients, or even in cases of refractory disease.