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VALIDITY EXPIRED
personal data approved: 2022. VI. 03.
Personal data
name Zsófia Hegedűs
name of institution
doctoral school
SzTE Doctoral School of Pharmaceutical Sciences (Supervisor)
SzTE Theoretical Medicine Doctoral School (Announcer of research topic)
the share of work in the different doctoral schools. SzTE Doctoral School of Pharmaceutical Sciences 50%
SzTE Theoretical Medicine Doctoral School 50%
Contact details
E-mail address hegedus.zsofiamed.u-szeged.hu
Academic title
scientific degree, title Ph.D.
year degree was obtained 2017
discipline to which degree belongs pharmaceutics
institution granting the degree University of Szeged
Employment
2019 - University of Szeged
other (not specified) (tanársegéd)
Thesis topic supervisor
number of doctoral students supervised until now
number of students who fulfilled course requirements
students who obtained their degrees:
present PhD students:
(50%) Vencel László Petrovicz (PhD) (2025/08)  DSPS-SzTE
  Thesis topic proposals
Research
research area Inhibition of protein-protein interactions, peptide chemistry, non-natural folding oligomers, dynamic covalent chemistry, non-ribosomal in vitro evolution methods
research field in which current research is conducted pharmaceutics
Publications
2022

Srdanović Sonja, Hegedüs Zsofia, Warriner Stuart L., Wilson Andrew J.: Towards identification of protein–protein interaction stabilizers via inhibitory peptide-fragment hybrids using templated fragment ligation, RSC CHEMICAL BIOLOGY
type of document: Journal paper/Article
language: English
URL 
2022

Hobor Fruzsina, Hegedüs Zsófia, Ibarra Amaurys Avila, Petrovicz Vencel, Bartlett Gail, Sessions Richard Barry, Wilson Andrew, Edwards Thomas A: Understanding p300-transcription factor interactions using sequence variation and hybridization, RSC CHEMICAL BIOLOGY
type of document: Journal paper/Article
language: English
URL 
2021

Hegedüs Zsófia, Hóbor Fruzsina, Shoemark Deborah K., Celis Sergio, Lian Lu-Yun, Trinh Chi H., Sessions Richard B., Edwards Thomas A., Wilson Andrew J.: Identification of β-strand mediated protein–protein interaction inhibitors using ligand-directed fragment ligation, CHEMICAL SCIENCE 12: (6) pp. 2286-2293.
type of document: Journal paper/Article
language: English
URL 
2021

Celis Sergio, Hobor Fruzsina, James Thomas, Bartlett Gail J., Ibarra Amaurys A., Shoemark Deborah K., Hegedüs Zsófia, Hetherington Kristina, Woolfson Derek N., Sessions Richard B., Edwards Thomas A., Andrews David M., Nelson Adam, Wilson Andrew J.: Query-guided protein–protein interaction inhibitor discovery, CHEMICAL SCIENCE 12: (13) pp. 4753-4762.
type of document: Journal paper/Article
language: English
URL 
2020

Turalic Amila, Dedibegovic Jasmina, Hegedus Zsofia, Martinek Tamas A.: DPP-4 Cleaves alpha/beta-Peptide Bonds: Substrate Specificity and Half-Lives, CHEMBIOCHEM 21: (14) pp. 2060-2066.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL 
2020

Hetherington Kristina, Hegedus Zsofia, Edwards Thomas A., Sessions Richard B., Nelson Adam, Wilson Andrew J.: Stapled Peptides as HIF-1 alpha/p300 Inhibitors: Helicity Enhancement in the Bound State Increases Inhibitory Potency, CHEMISTRY-A EUROPEAN JOURNAL 26: (34) pp. 7638-7646.
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL 
2019

Hegedus Zsofia, Grison Claire M., Miles Jennifer A., Rodriguez-Marin Silvia, Warriner Stuart L., Webb Michael E., Wilson Andrew J.: A catalytic protein-proteomimetic complex: using aromatic oligoamide foldamers as activators of RNase S., CHEMICAL SCIENCE 10: (14) pp. 3956-3962.
type of document: Journal paper/Article
number of independent citations: 7
language: English
URL 
2019

Ibarra Amaurys A., Bartlett Gail J., Hegedus Zsofia, Dutt Som, Hobor Fruzsina, Horner Katherine A., Hetherington Kristina, Spence Kirstin, Nelson Adam, Edwards Thomas A., Woolfson Derek N., Sessions Richard B., Wilson Andrew J.: Predicting and Experimentally Validating Hot-Spot Residues at Protein-Protein Interfaces, ACS CHEMICAL BIOLOGY 14: (10) pp. 2252-2263.
type of document: Journal paper/Article
number of independent citations: 15
language: English
URL 
2017

Bartus E, Hegedüs Z, Wéber E, Csipak B, Szakonyi G, Martinek TA: De Novo Modular Development of a Foldameric Protein-Protein Interaction Inhibitor for Separate Hot Spots: A Dynamic Covalent Assembly Approach, CHEMISTRYOPEN 6: (2) pp. 236-241.
type of document: Journal paper/Article
number of independent citations: 7
language: English
URL 
2013

Hegedus Z, Weber E, Kriston-Pal E, Makra Ildikó, Czibula A, Monostori E, Martinek TA: Foldameric alpha/beta-Peptide Analogs of the beta-Sheet-Forming Antiangiogenic Anginex: Structure and Bioactivity, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 135: (44) pp. 16578-16584.
type of document: Journal paper/Article
number of independent citations: 24
language: English
URL 
Number of independent citations to these publications:58 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
20
number of scientific publications:
20
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
1 
number of independent citations to scientific publications and creative works:
387


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )