Short peptide assemblies to form extracellular matrices promoting spinal coord injury

Eötvös Loránd Tudományegyetem

Hevesy György Kémia Doktori Iskola

Beke-Somfai Tamás

kémiai tudományok

The Biomolecular Self-assembly “Momentum” research group ( http://bionano.ttk.hu/) is looking for a PhD student in chemistry, to conduct design, synthesis, and biophysical characterization of novel peptide scaffolds, based on our recent self-assembling constructs. An emerging signaling strategy for cells is to use nanostructures that could target specific cells to deliver a therapeutic cargo or materials functioning as bioactive scaffolds in the extracellular space. Cell-signaling materials that trigger the regeneration of tissues mimic the fibrillar components of natural extracellular matrices. Within the project we aim to use natural and non-natural scaffolds for use in biomedical applications, potentially for improving neuron-neuron interactions and spinal coord injury.
For reference see our recent related studies : El Battioui et al. 2024. Nat. Commun. 15 3424 Nagaraj et al. 2022 ACS Applied Materials & Interfaces 14 (50), 55320-55331 and recent literature: Álvarez et al. 2021 Science, 374 6569, pp 848

1 fő

2026-05-31

English